If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




schemaVersion:


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 represent shares of Common Stock held directly by Frazier Life Sciences X, L.P. The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 represent shares of Common Stock held directly by Frazier Life Sciences X, L.P. The percentage listed in row 13 is calculated based on 53,240,888 shares of the Issuer's Common Stock outstanding as of May 7, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on May 14, 2026.


SCHEDULE 13D


 
Frazier Life Sciences Public Fund, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P., GP of Frazier Life Sciences Public Fund, L.P.
Date:05/21/2026
 
FHMLSP, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P.
Date:05/21/2026
 
FHMLSP, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C.
Date:05/21/2026
 
Frazier Life Sciences X, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P., GP of Frazier Life Sciences X, L.P.
Date:05/21/2026
 
FHMLS X, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P.
Date:05/21/2026
 
FHMLS X, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C.
Date:05/21/2026
 
Frazier Life Sciences XI, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P., GP of Frazier Life Sciences XI, L.P.
Date:05/21/2026
 
FHMLS XI, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P.
Date:05/21/2026
 
FHMLS XI, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C.
Date:05/21/2026
 
Frazier Life Sciences XII, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C., GP of FHMLS XII, L.P., GP of Frazier Life Sciences XII, L.P.
Date:05/21/2026
 
FHMLS XII, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C., GP of FHMLS XII, L.P.
Date:05/21/2026
 
FHMLS XII, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C.
Date:05/21/2026
 
James N. Topper
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, Attorney-in-Fact for Patrick J. Heron, pursuant to Power of Attorney
Date:05/21/2026
 
Patrick J. Heron
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, Attorney-in-Fact for Patrick J. Heron, pursuant to Power of Attorney
Date:05/21/2026
ex-10-05212026_080514.htm

EXHIBIT 10.1


Transactions Relating to the Common Stock of the Issuer During the Past Sixty (60) Days


The following table sets forth all transactions relating to the Common Stock of the Issuer that were effected during the past sixty (60) days by the applicable Reporting Person.


Reporting Person Name

Date of Event

Type of Transaction

Number of Shares

Price Per Share

Footnote

FLSPF

5/6/2026

Sale

90,005

$26.7668

(1)

FLS X

5/6/2026

Sale

30,837

$26.7668

(1)

FLS XI

5/6/2026

Sale

10,490

$26.7668

(1)

FLS XII

5/6/2026

Sale

473

$26.7668

(1)

FLSPF

5/19/2026

Sale

2,048,592

$26.7815

(2)

FLS X

5/19/2026

Sale

701,880

$26.7815

(2)

FLS XI

5/19/2026

Sale

238,765

$26.7815

(2)

FLS XII

5/19/2026

Sale

10,763

$26.7815

(2)


(1)

These shares were sold in multiple transactions at prices ranging from $26.76 to $26.785, inclusive. The Reporting Person undertakes to provide to the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.


(2)

These shares were sold in multiple transactions at prices ranging from $26.77 to $26.825, inclusive. The Reporting Person undertakes to provide to the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.




ex-99-05212026_080515.htm

EXHIBIT 99.1


JOINT FILING AGREEMENT


Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13G need be filed with respect to the ownership by each of the undersigned of Shares of Common Stock of KalVista Pharmaceuticals, Inc.

 


Date:  May 21, 2026

FRAZIER LIFE SCIENCES PUBLIC FUND, L.P.

By: FHMLSP, L.P., its General Partner

By: FHMLSP, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLSP, L.P.

By: FHMLSP, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLSP, L.L.C.


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FRAZIER LIFE SCIENCES X, L.P.

By: FHMLS X, L.P., its General Partner

By: FHMLS X, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLS X, L.P.

By: FHMLS X, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLS X, L.L.C.


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FRAZIER LIFE SCIENCES XI, L.P.

By: FHMLS XI, L.P., its General Partner

By: FHMLS XI, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLS XI, L.P.

By: FHMLS XI, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLS XI, L.L.C.


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FRAZIER LIFE SCIENCES XII, L.P.

By: FHMLS XII, L.P., its General Partner

By: FHMLS XII, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLS XII, L.P.

By: FHMLS XII, L.L.C., its General Partner


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

FHMLS XII, L.L.C.


By: /s/ Jennifer Martin

Jennifer Martin, Chief Financial Officer



Date:  May 21, 2026

By: *

James N. Topper



Date:  May 21, 2026

By: *

Patrick J. Heron



Date:  May 21, 2026

By: /s/ Jennifer Martin

Jennifer Martin, as Attorney-in-Fact


* This Joint Filing Agreement was executed by Jennifer Martin on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which was filed with the SEC on January 27, 2026.